세미나 및 강연

Abstract:

Nuclear medicine imaging technique including PET/CT and SPECT is a powerful molecular imaging tool for the investigation of oncological and neurological investigation of human body and brain. In addition, multi-center clinical trial is a hot issue for both drug efficacy demonstration and the cost-effectiveness by PET imaging in the context of national financial difficulties in healthcare. Generally, different PET scanners exhibit different sensitivity and spatial resolution. Therefore, inter-institutional and intra-institutional harmonization of PET scanner performance is a prerequisite for multi-center trial. Therefore, we present harmonization methods for oncological and neurological PET images between multiple PET scanners for the comparison and compatibility between multiple scanners within-institute and cross-institute. Since PET scanners (both dedicated PET and PET/CT) have been developed, there are a variety of PET scanners with/without sophisticated features (e.g., time of flight, and point spread function). We developed both harmonization methods for body and brain PET images using ACR phantom and Hoffman phantom-based method, respectively. In addition, we also developed quantitative analysis method for PET using partial volume correction, and that for SPECT using subtraction-based method termed SISCOM. On the basis of these techniques, we could analyze nuclear medicine imaging in a scanner-independent and quantitative manner.

Speaker Bio:

Prof. Dr. Jungsu Oh graduated from School of Electrical Engineering, Seoul National University, and received his Master and Doctoral Degrees from Department of Biomedical Engineering, Seoul National University. Prof. Dr. Oh improved his profound knowledge on medical imaging during his research fellowship in Seoul National University, National Cancer Center, and Harvard Medical School. Prof. Dr. Oh was a Research Assistant Professor of Seoul National University. Now Prof. Dr. Oh is an Associate Professor at Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine. For the last 15 years, Prof. Dr. Oh is a specialist in both PET/SPECT and MRI image processing and focuses on a number of quantification issues in medical imaging, and has involved in many neurological, psychiatric, oncological imaging studies (Schizophrenia, OCD, Alzheimer Disease, Parkinson Disease, Epilepsy, and various Cancers) using many imaging moralities (PET, SPECT, Diffusion/Functional/Structural MRIs).